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- That part of a chemical reactionA process in which one or more substances, the reactant or reactants, change into one or more different substances, the products; chemical change involves rearrangement, combination, or separation of atoms. Also called chemical change. in which a reactantA substance consumed by a chemical reaction. gains electrons; simultaneous oxidationThat part of a chemical reaction in which a reactant loses electrons; simultaneous reduction of a reactant must occur. of a reactant must occur.