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- substitution reaction
- A reaction in which one atomThe smallest particle of an element that can be involved in chemical combination with another element; an atom consists of protons and neutrons in a tiny, very dense nucleus, surrounded by electrons, which occupy most of its volume. or functional groupA set of atoms in a molecule that confer on the molecule a characteristic set of physical and chemical properties. is replaced by another (distinguished from an addition reactionA reaction in which two moleular-scale species combine to form a single molecular-scale species (distinguished from a substitution reaction).).